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help me clarify DKA hyper and hypoglycemiaRating: (votes: 0) Hypo/hyperglycemia refer explicitly to the serum blood state and amount of available blood glucose. It is either defined as too high (hyper), too low (hypo), or normal (euglycemia). DKA is a state where the blood sugar becomes too high (hyper) in mostly Type 1 (IDDM) diabetics. Since their is complete failure for the pancreatic B-cells to produce any insulin. There is no insulin to move that large amount of sugar from the blood to the cells, so the cells cannot under go their normal metabolic functions, thus they undergo anaerobic metabolism to sustain themselves which includes ketogenesis which is the break down of fatty acids into ketone bodies for cellular respiration and metabolism since there is no glucose for making ATP. Ketones are not excreted as readily and can build up, and since they are an acid (keto-acid) they can manifest in a patient as ketone induced metabolic acidosis. In short DKA is a manifestation of uncontrolled hyperglycemia usually presenting in IDDM patients. Comment:
Mrmedical, thank you for your input. However, that is the way I thought before- "DKA is a state where the blood sugar becomes too high (hyper)." But here is what made me wonder about that logic... The reason body starts metabolizing fat is because the cells aren't getting sugar. But the cells aren't getting sugar in both situations; hyper (in type 1) or hypoglycemia. Why doesn't hypoglycemia cause fat metabolizing?
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Quote from unsaint77Mrmedical, thank you for your input. However, that is the way I thought before- "DKA is a state where the blood sugar becomes too high (hyper)." But here is what made me wonder about that logic... The reason body starts metabolizing fat is because the cells aren't getting sugar. But the cells aren't getting sugar in both situations; hyper (in type 1) or hypoglycemia. Why doesn't hypoglycemia cause fat metabolizing?
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Your best bet is go back to your physiology book.
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Quote from unsaint77Mrmedical, thank you for your input. However, that is the way I thought before- "DKA is a state where the blood sugar becomes too high (hyper)." But here is what made me wonder about that logic... The reason body starts metabolizing fat is because the cells aren't getting sugar. But the cells aren't getting sugar in both situations; hyper (in type 1) or hypoglycemia. Why doesn't hypoglycemia cause fat metabolizing?
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so what you are saying what psu_213 is saying- with hypoglycemia, DKA is not a concern because the person will die from hypoglycemia before the DKA happens. Is that correct?
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